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Study on the evaluation of the safety and efficacy of Sofosbuvir in participants with mild coronavirus in outpatients (COVID-19)

Comparison of the therapeutic effect of Sofosbuvir with Control group in outpatients with Covid-19 referred to outpatient clinics in Ahvaz

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201127049505N1
Enrollment
360
Registered
2021-02-06
Start date
2020-12-28
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19. COVID-19

Interventions

Intervention 1: Intervention group:400mg of Sofosbovir and Vitamin B1300 control group. Intervention 2: Control group: Vitamin B1300.

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Outpatients presented with positive PCR and mild clinical signs without pulmonary involvement on CT scan As defined by patient with sore throat dry cough loss of sense of smell and taste nausea and vomiting O2 Sat = 95 T <38 RR <24 stable pulse and blood pressure body aches

Exclusion criteria

Exclusion criteria: y>18 Organ transplant Severe skin history including TEN or Steven JohnsonAllergy to the studied drug The patient has previously been treated with this drug for other reasons Hepatitis C Not able to take pills Lack of awareness Be treated with anticonvulsant drugs Have fever and respiratory symptoms from 2 weeks ago Be treated with immunosuppressive drugs Be pregnant or breastfeeding 1 month ago received antiviral drugs for Covid-19 ESRD Advance CKD Advance liver disease Pulmonary Advance Disease Cardiac Advance Disease Advance Disease Hematology Solid tumor Cancer of neurological diseases such as CVA your situationG6PD deficient Be pregnant or breastfeeding

Design outcomes

Primary

MeasureTime frame
Shortness of breath. Timepoint: day 14 or sooner at the discretion of the physician. Method of measurement: Clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Hadad Zade Shoushtary

Ahvaz University of Medical Sciences

Drmahtab.moeinpour@yahoo.com+98 21 3322 1251

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026