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The effect of triamcinolone and Q10 coenzyme in the treatment of oral lichen planus

Evaluating the effect of a combined mouthwash of triamcinolone acetonide 0.1% and Q10 coenzyme in the treatment of oral lichen planus

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201127049502N1
Enrollment
18
Registered
2020-12-01
Start date
2020-12-20
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral lichen planus. Lichen planus

Interventions

Intervention 1: Intervention group: In this group, patients receive 0.1% triamcinolone mouthwash. mouthwash will be used four times a day in the amount of 15 ml each time (by the measure) and then pat

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with symptomatic oral lichen planus (erosive or atrophic form) who have a sense of burning or pain. The diagnosis is clinical (Wickham striae or papules) and in cases in which a definitive diagnosis of the lesion is difficult, a histopathological evaluation will be used. The patient should not have used topical corticosteroid treatments in the last two weeks or systemic corticosteroids in the last month. The patient should not have used analgesics and anesthetics.

Exclusion criteria

Exclusion criteria: Patients with lichenoid lesions caused by medication or dental materials Pregnant or lactating patients Patients with other lesions such as leukoplakia and systemic lupus in conjunction with lichen planus History of malignancy Non-cooperative patients and patients who do not use drugs

Design outcomes

Primary

MeasureTime frame
Severity and size of the lesions based on REU index. Timepoint: baseline(day0), day15, day30. Method of measurement: Graded tongue blade.;Amount of healing based on E?cacy Index. Timepoint: baseline(day0), day15, day30. Method of measurement: formula.;Severity of burning sensation based on VAS Index. Timepoint: baseline(day0), day15, day30. Method of measurement: Scoring by the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Rahimzamani

Shahid Beheshti University of Medical Sciences

zamani_arezoo@yahoo.com+98 21 2990 2311

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026