acute phase of diabetic ketoacidosis. Endocrine, nutritional and metabolic diseases.
Conditions
Interventions
Intervention 1: Intervention group 1: Children who in the first 6 hours of treatment, in addition to receiving short-term standard insulin drip, receive a long dose of subcutaneous insulin effect of D
Sponsors
Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 15 Years
Inclusion criteria
Inclusion criteria: age between 2 to 15 years old acute diabetic ketoacidosis : BS> 200 mg / dL, PH <7.30 , HCO3 <15 mEq / L ,urinary ketone positive
Exclusion criteria
Exclusion criteria: • Reluctance to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of exit from the acute phase of diabetic ketoacidosis.Exclusion from the acute phase in this study is a condition in which the serum level is PH> 7.30, HCO3> 15mEq / L, normal serum electrolytes, the patient is conscious and does not vomit. Timepoint: From the time of diagnosis of diabetic ketoacidosis to the time of exit from the acute phase. Method of measurement: Time to hour. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining the average length of hospital stay in the PICU. Timepoint: From the beginning of hospitalization to the time of leaving the PICU. Method of measurement: Time to hour.;Evaluation of side effect from drug use during the study period: Hypoglycemia. Timepoint: From the beginning of the acute phase of diabetic ketoacidosis until the exit of the acute phase. Method of measurement: Frequent laboratory and glucotest monitoring of blood plasma.;Evaluation of side effects due to drug use during the study period: Hypokalemia. Timepoint: From the beginning of the acute phase of diabetic ketoacidosis until the exit of the acute phase. Method of measurement: Laboratory measurement of plasma potassium levels every three hours.;Cerebral edema. Timepoint: From starting treatment for diabetic ketoacidosis to having criteria for exiting the acute phase. Method of measurement: Have any signs or symptoms of high intracranial pressure on clinical examination and vital signs according to international standards. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVictoria Chegini
Qazvin University of Medical Sciences
Outcome results
None listed