Comparison of the effect of high protein diet in people at risk of premature menopause

Comparison of the effect of three high animal protein diet , high plant protein and common protein on indicators related to ovarian aging (premature menopause) in people at risk of premature ovarian failure: a clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201124049481N1

Enrollment

Registered

2021-08-12

Start date

2021-09-23

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature menopause. Premature menopause

Interventions

Intervention 1: Group 1: Animal high protein diet. Intervention 2: Intervention group: Intervention group: high protein plant diet.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women in their 20s and 40s who have stopped menstruating or two to three periods a year and have Anti Mullerian hormone level as defined in the scientific definitions and FSH level above 10 IU / L. are at risk for premature menopause Normal creatine or GFR levels above 70 No change in supplements (antioxidants) Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Having a history of radiotherapy Having a history of ovarian surgery

Design outcomes

Primary

Measure	Time frame
Serum level of Anti Mullerian Hormone. Timepoint: It will be measured at the beginning and end of the study. Method of measurement: It will be measured by ELISA method.	—

Secondary

Measure	Time frame
Premature menopause. Timepoint: Not applicable. Method of measurement: Based on the AMH level according to the table mentioned in the.;Serum level of Estrogen. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Progestron. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Follicle-stimulating hormone (FSH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Luteinizing Hormone (LH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Inhibin A. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Inhibin B. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of C-Reactive Protein. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Sonography. Timepoint: At the beginning and end of the study in terms of ovarian volume, number of antral follicles, antral thickness. Method of measurement: Ultrasound device.	—

Measure

Time frame

Premature menopause. Timepoint: Not applicable. Method of measurement: Based on the AMH level according to the table mentioned in the.;Serum level of Estrogen. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Progestron. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Follicle-stimulating hormone (FSH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Luteinizing Hormone (LH). Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Inhibin A. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of Inhibin B. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Serum level of C-Reactive Protein. Timepoint: At the beginning and 6 months after starting the diet. Method of measurement: It will be measured by ELISA method.;Sonography. Timepoint: At the beginning and end of the study in terms of ovarian volume, number of antral follicles, antral thickness. Method of measurement: Ultrasound device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarjan bedakhanian

Shahid Beheshti University of Medical Sciences

marjanbadakhanian@ymail.com0000000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026