outpatient covid19 infected individuals. COVID-19
Conditions
Interventions
Intervention 1: Intervention group: Levamisole 50 mg/day for ten days + routine management for covid19 based on national protocol (Hydroxychloroquine tablets 200 mg daily, acetaminophen 500 mg every 6
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age 18 years or older Positive RT PCR test for COVID-19 Full consent and acceptance of the patient or his companion for taking the drug Patient traceability Women should not become pregnant for 30 days after the end of the study patients should not take levamisole for five days before entering the study (because the half-life of ?the drug is 16 hours)
Exclusion criteria
Exclusion criteria: Another justifying cause (such as a bacterial or fungal infection) for the patient's symptoms Allergic reaction to levamisole Use of antibiotics other than those used to treat COVID-19 Shortness of breath due to cardiogenic pulmonary edema Lactation pregnancy Patients with unstable hemodynamics; History of cirrhosis, hepatitis, or severe liver disease, GFR ?less than 30 ml/min Patients receiving chemotherapy for cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The general condition of the patient. Timepoint: Days 1,3,5,7,9,14. Method of measurement: Verbal Numeric Scale(VNS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital admission. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Mortality rate. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Cough. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Sore throat. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Dyspnea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Myalgia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Diarrhea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Vomiting. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Nausea. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Anosmia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Dysgeusia. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Headache. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone.;Fever. Timepoint: Day 1,3,5,7,9,14. Method of measurement: telephone. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Aminianfar
Artesh University of Medical Sciences
Outcome results
None listed