Chemotherapy induced liver injury. Injury of liver
Conditions
Interventions
Intervention 1: Intervention group: The first treatment group receives two 140 mg silymarin tablets one week before the start of the chemotherapy course and is taken daily for two months after the che
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients aged 30 to 60 years Ability to take the drug orally Definitive diagnosis of breast cancer that has chemotherapy indications and has not yet received its chemotherapy drug Liver tests are normal before the intervention Indication of treatment with chemotherapy regimen
Exclusion criteria
Exclusion criteria: pregnant and breastfeeding liver metastasis and liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function test. Timepoint: Measurement of liver enzymes at the beginning of the study (before the intervention) and 3 and 6 weeks after the start of silymarin. Method of measurement: Lab data. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSafoora Sadat Erfanian
Esfahan University of Medical Sciences
Outcome results
None listed