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Comparison of rivaroxaban and enoxaparin in the prevention of recurrent venous thromboembolism

Comparison of rivaroxaban and enoxaparin in the prevention of recurrent venous thromboembolism in patients with nonhematologic cancer

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201123049469N1
Enrollment
50
Registered
2020-12-22
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonhematologic Cancers. Embolism and thrombosis of unspecified artery

Interventions

Intervention 1: Intervention group: Oral rivaroxaban treatment group, 15 mg every 12 hours for the first three weeks and then 20 mg daily / Axabin
Abidi Company, Tehran. Intervention 2: Intervention group: The dose of enoxaparin (Lovenox
Osweh Pharmacy, Tehran) was 1 mg per kg body weight, but because 60 or 80 mg ampoules were used, depending on the patient's weight, 60 or 80 mg of the drug every 12 hours as the following injection It

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Existence of active cancer with Venous thromboembolism The age range is between 18-75 years Tendency to participate in the study

Exclusion criteria

Exclusion criteria: Smoking, alcohol and drug abuse Lack of sufficient and appropriate evidence for the occurrence of early Venous thromboembolism Diagnosis of thrombophilic conditions Prescribe any anticoagulant drug excepting Enoxaparin or Rivaroxaban (for example Heparin, Warfarin, Dabigatran, Apixaban, and Edoxaban)

Design outcomes

Primary

MeasureTime frame
Recurrence of VTE (Venous thromboembolism) is deep vein thromboembolism (DVT) or pulmonary embolism (PE) according to the report of CT scan of the pulmonary arteries and color Doppler ultrasound of the lower extremity to be reported by the radiologist. Timepoint: At the beginning of the study (before the intervention) and 6 months later. Method of measurement: according to the report of CT scan of the pulmonary arteries and color Doppler ultrasound of the lower extremity to be reported by the radiologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfrooz Kargaran Dehkordi

Ahvaz University of Medical Sciences

karegaran.a@ajums.ac.ir+98 61 3321 4578

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026