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Comparison of pregnancy outcomes in 3- and 5-day frozen embryo transfer cycles with blastocysts in normoresponder women

Comparison of pregnancy outcomes in 3- and 5-day frozen embryo transfer cycles with blastocysts in normoresponder women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201121049457N3
Enrollment
148
Registered
2026-02-12
Start date
2026-02-20
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: On the transfer day, a 5-day embryo is transferred. Intervention 2: Control group: On the transfer day, 3- and 5-day embryos are transferred.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 41 Years

Inclusion criteria

Inclusion criteria: Infertile women (18-41 years old) Normal uterine cavity Normal ovarian response to stimulation Women undergoing infertility treatment with IVF or microinjection and having at least 3 frozen embryos No history of endometriosis or endocrine disorders and no hysteroscopic surgery No severe male factor infertility No poor ovarian response (less than or equal to 3 oocytes) or excessive ovarian response (more than 20 oocytes)

Exclusion criteria

Exclusion criteria: Cervical insufficiency Endometrial thickness less than 7 mm on the day of embryo transfer Unwillingness to continue the study

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy rate. Timepoint: 2 week after embryo transfer. Method of measurement: BHCG serum.;Clinical pregnancy rate. Timepoint: 6 weeks after embryo transfer. Method of measurement: Sonography.

Secondary

MeasureTime frame
Abortion rate. Timepoint: Before 20 weeks of pregnancy. Method of measurement: Bleeding and expulsion of the fetus.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Amirian

Mashhad University of Medical Sciences

amirianm@mums.ac.ir+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026