Study of the effect of comprehensive oral care program and combination of toothbrush and mouthwash with chlorhexidine 0.2% on the incidence of ventilator-associated pneumonia and oral health status in patients undergoing mechanical ventilation.

Comparison the effect of comprehensive oral care program and combination of toothbrush and mouthwash with chlorhexidine 0.2% on the incidence of ventilator-associated pneumonia and oral health status in patients undergoing mechanical ventilation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201121049455N1

Enrollment

Registered

2020-12-10

Start date

2020-09-07

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia. Pneumonia due to other Gram-negative bacteria

Interventions

Intervention 1: Intervention group: Comprehensive Oral Care Plan: The Comprehensive Oral Care Plan was designed based on previous studies and included performing the following 5 minutes of oral care e

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age range 65-18 years On the second day of the patient's hospitalization Achieve a score less than or equal to 5 of the MCPIS criteria No severe damage to face and mouth No chronic disease and defective immune system No movable dentures The patient is not pregnant Normal coagulation status

Exclusion criteria

Exclusion criteria: Performing a tracheostomy procedure during the study Removal or replacement of endotracheal tube during the study Detach from mechanical ventilation before 96 hours Clearance from the ward Allergy to chlorhexidine Reluctance to continue the study by the legal guardian Patient death Evidence of signs and symptoms of aspiration after the start ofthe study according to the patient file

Design outcomes

Primary

Measure	Time frame
Ventilator-dependent pneumonia score. Timepoint: Ventilator-dependent pneumonia score before intervention and end of fifth day. Method of measurement: Clinically modified pneumonia scale.;Oral health status. Timepoint: Beck oral assessment scale score during five days of study. Method of measurement: Beck Oral Assessment Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFariba Yaghobinia

Zahedan University of Medical Sciences

yaghoubinia@gmail.com+98 54 3343 0059

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026