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Effect of intravitreal triamsinolone injection on macular anatomy

Effect of adjuvant intraoperative intravitreal triamcinolone on the optical coherence tomography-wise macular anatomy following vitrectomy for epiretinal membrane: a Randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201120049450N4
Enrollment
40
Registered
2024-04-12
Start date
2023-12-11
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epiretinal membrane. Puckering of macula, unspecified eye

Interventions

Intervention 1: Intervention group: patients with idiopathic ERM who underwent pars plana vitrectomy and membrane peeling with intravitreal injection of triamcinolone acetonide (IVTA). Intervention 2:

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with idiopathic epiretinal membrane (ERM) Decreased vision(BCVA:20/400-20/40) or metamorphopsia Central foveal thickness more than 320 micron

Exclusion criteria

Exclusion criteria: Previous retinal surgery, retinal detachment, Age related macular degeneration, diabetic retinopathy, retinal vascular occlusion, uveitis vitreous hemorrhage, trauma ocular tumors, glaucoma optic atrophy, fibrotic epiretinal membrane, macular pathologies other than ERM, significant cataract corneal opacity incomplete chart records.

Design outcomes

Primary

MeasureTime frame
Central subfield thickness. Timepoint: before operation and 1, 3, 6 and 12 months after operation. Method of measurement: macular OCT.;Best corrected visual acuity. Timepoint: before operation and 1, 3, 6 and 12 months after operation. Method of measurement: snellen chart.

Secondary

MeasureTime frame
Retinal sublayers. Timepoint: before operation and 1, 3, 6 and 12 months after operation. Method of measurement: optical coherence tomography.;Intraocular pressure. Timepoint: before operation and 1, 3, 6 and 12 months after operation. Method of measurement: Tonometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEhsan Namvar

Shiraz University of Medical Sciences

Namvar.e@gmail.com+98 71 3629 1470

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026