Depressive phase of bipolar patients type one and two. Bipolar disorder, current episode depressed, mild or moderate severity
Conditions
Interventions
Intervention 1: Intervention group: Pentoxifylline tablets, 400 mg, one daily, in the morning, for two months, a product of Amin Pharmaceutical Company. Intervention 2: Control group: In addition to
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with type 1 and 2 bipolar disorder with an age range of 18 to 60 years in the depressive phase Diagnosis of type 1 and 2 bipolar disorder based on DSM-V criteria by a psychiatrist Have at least five classes of education
Exclusion criteria
Exclusion criteria: Existence of psychotic symptoms Existence of another psychiatric disorder Existence of hypothyroidism History of cardiovascular disease Pregnancy or breastfeeding Existence of hepatic failure Peptic ulcer Take antiplatelet drugs or anticoagulants Receiving non-steroidal anti-inflammatory drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression score in Bipolar Depression Rating Scale questionnaire. Timepoint: At the beginning of the study, weeks 4 and 8 of the study. Method of measurement: Bipolar Depression Rating Scale questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life score. Timepoint: Before the study, weeks 4 and 8 after the study. Method of measurement: 20-item BDRS questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHajar Salimi
Esfahan University of Medical Sciences
Outcome results
None listed