The effect of adding fenofibrate to phenobarbital in the treatment of prolonged neonatal jaundice

Comparison of the effect of adding a single dose of fenofibrate to phenobarbital in the treatment of prolonged neonatal jaundice with phenobarbital alone

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201118049433N1

Enrollment

Registered

2020-12-10

Start date

2020-08-09

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged neonatal jaundice.

Interventions

Intervention 1: In this group, phenobarbital tablets with a dose of 10 mg/kg on the first day and then with a dose of 5 mg/kg until the fifth day, are given orally daily. Intervention 2: Intervention

Eligibility

Sex/Gender

All

Age

14 Days to 40 Days

Inclusion criteria

Inclusion criteria: Infants who are full-term (gestational age between 37 and 41 weeks) All infants between the ages of 14 and 40 days All infants weighing between 2500 and 4000 grams Infants who are breastfed All infants with total bilirubin 10 to 20 mg/dL Infants who show no signs of hemolysis on a blood test Infants who do not have symptoms of an infectious disease or any abnormality

Exclusion criteria

Exclusion criteria: Infants who are dehydrated Infants who test positive for Coombs Infants with indirect bilirubin more than 2 mg/dL

Design outcomes

Primary

Measure	Time frame
Total bilirubin. Timepoint: At the beginning of the study (before the intervention) and 7 days after the start of the procedure. Method of measurement: Bilirubin meter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Golshan Tafti

Islamic Azad University

mgolshan035@gmail.com+98 35 3725 8060

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026