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Effect of dexamethasone on tooth extraction

Effect of local dexamethasone on pain, swelling and trismus after impacted third molar extraction

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201117049418N1
Enrollment
72
Registered
2020-11-20
Start date
2012-02-05
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

third molar extraction.

Interventions

Intervention 1: Intervention group: Group 1 received dexamethasone powder 4 mg inside the alveolar socket after washing and before flap suturing. Intervention 2: Intervention group: group 2 received d

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: individuals with painful impacted lower third molar aged over 18 and less than 35 third molar mesioangular deviation in imaging

Exclusion criteria

Exclusion criteria: pregnant and lactating women systemic diseases such as diabetes and hypertension analgesic and anti-inflammatory drug consumption such as NSAIDs and GCs at least one week before surgery existing or developed infectious conditions such as abscess and surgical site infection antibiotic use at least one week before surgery known psychiatric disorders surgery duration longer than 30 minutes.

Design outcomes

Primary

MeasureTime frame
Patient’s severity of pain was measured by Visual Analogue Scale (VAS). Timepoint: surgery day, two days after surgery and then one week after surgery. Method of measurement: This is a 100-mm ruler, which the patient marks the pain severity on it from zero (painless) to 100 (maximum pain). After receiving training, the patients expressed their severity of pain and recorded it in terms of cm.-.;Swelling To measure swelling, the distance of tragus to the corner of the lip and tragus to gonion[. Timepoint: surgery day, two days after surgery and then one week after surgery. Method of measurement: swelling, the distance of tragus to the corner of the lip and tragus to gonion[17] was measured by a standard cloth ruler, and these values were summed and divided by two to obtain the swelling mean in the surgery side in millimeter.-.;Trismus In order to assess the maximal mouth opening, patients opened their mouth straight so that they did not have jaw deflection, pain and discomfort. Timepoint: surgery day, two days after surgery and then one week after surgery. Method of measurement: Maximal mouth opening was recorded by measuring the distance between the incisal edges of the upper and lower central teeth using a coulisse ruler in millimeter.

Countries

United States of America

Contacts

Public ContactFarshad Khosraviani

Tehran University of Medical Sciences

farshadkhosraviani@gmail.com+1 949-771-5704

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026