Effect of local Mitomycin C in caustic esophageal stricture

Evaluating the effect of local Mitomycin C jelly on esophageal stricture caused by caustic ingestion

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201116049399N1

Enrollment

Registered

2020-12-31

Start date

2020-11-30

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caustic esophageal stricture. Burn of esophagus

Interventions

Intervention 1: Intervention group: Patients who receive topical Mitomycin after endoscopic dilatation of caustic esophageal stricture.For patients in this group, esophageal dilatation with Savarry Gi

Eligibility

Sex/Gender

All

Age

No minimum to 21 Years

Inclusion criteria

Inclusion criteria: Patients under 21-year-old Caustic ingestion Esophageal stricture based on barium swallow study or clinical examination Informed consent of patients or his guardian

Exclusion criteria

Exclusion criteria: Previous esophageal surgery

Design outcomes

Primary

Measure	Time frame
Dysphagia. Timepoint: Every two weeks after starting the study. Method of measurement: Clinical grading.;Number of Dilatation. Timepoint: Every two weeks after starting the study. Method of measurement: The number of performed procedure.	—

Secondary

Measure	Time frame
Weight. Timepoint: every two weeks after starting the study. Method of measurement: ADE pediatric scale with 1 gram acuity.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Basirinezhad

Mashhad University of Medical Sciences

basirinezhadf971@mums.ac.ir+98 51 3605 7487

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026