Paclitaxel induced peripheral neuropathy. Polyneuropathy (diseases of several nerves) and other disorders of the peripheral nervous system
Conditions
Interventions
Intervention 1: Intervention group: Patients with taxol-induced peripheral neuropathy who take dolextin 60 daily for two weeks. at the beginning and the end of the test, the patient's TNF alphaf wil
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1- Women with breast cancer (according to the pathological tests and graphies) Treat with paclitaxel 80 mg once a week checked with Beck Depression Inventory (BDI-II) . not treated any other chemotherapy drugs with Life expectancy over than 6 months
Exclusion criteria
Exclusion criteria: Pregnant or breastfeeding women Women with a history of diabetes or peripheral vascular disease Woman with a history of liver and kidney disease Woman with a history of Psychiatric diseases such as bipolar disorder woman a history of peripheral nerve disease such as carpal tunnel
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reducing peripheral neuropathy pain. Timepoint: Evaluation of neuropathic pain at the beginning and end of the intervention with measurement of TNF at the beginning and end of the intervention in two parallel groups. Method of measurement: Using( The Brief Pain Inventory); ( National Cancer Institute-Common Toxicity Criteria); von Frey or monofilament test; Visual analog scale; TNF alpha ELISA Kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra rezaiyan
Kashan University of Medical Sciences
Outcome results
None listed