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Evaluation of various antibiotic regimens in recurrent urinary tract infections

Comparative study of prophylactic antibiotics twice a week with antibiotics every night in recurrent urinary tract infections in children

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201112049368N1
Enrollment
60
Registered
2020-12-11
Start date
2015-07-23
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent urinary tract infections. Urinary tract infection, site not specified

Interventions

Intervention 1: Intervention group: Consumption of 5 mg/kg cotrimoxazole twice a week for ten months. Intervention 2: Control group: Consumption of 10 mg/kg cephalexin daily for ten months.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 12 Years

Inclusion criteria

Inclusion criteria: Complete the consent form to participate in the project Children with grade 2 or higher reflux who need prophylactic antibiotics Patients in good general condition Resident of Mashhad or nearby cities that can be followed

Exclusion criteria

Exclusion criteria: Dissatisfaction with continued cooperation Migration Patients with impaired consciousness or mental retardation Patients cared for in orphanages Patients with a history of urinary tract stones History of hypersensitivity reaction to cotrimoxazole or cephalexin Do not refer for testing

Design outcomes

Primary

MeasureTime frame
The recurrence rate of urinary tract infection (asymptomatic and symptomatic). Timepoint: At the beginning of the study and then after receiving antibiotics, once a month for ten months. Method of measurement: Urine culture with more than 10 to the power of 5 colonies.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Taheri

Tehran University of Medical Sciences

amin.taheri2731@gmail.com+98 51 5422 2821

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026