Effect of Systemic Prednisolone and Topical Tranexamic Acid on Prevention of Rebleeding in Traumatic Hyphema

Comparison of the Effect of Systemic Prednisolone and Topical Tranexamic Acid on Prevention of Rebleeding in Patients with Traumatic Hyphema

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201110049345N1

Enrollment

Registered

2020-12-01

Start date

2018-08-23

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyphema. Hyphema

Interventions

Intervention 1: Patients with traumatic hyphema recived Topical Tranzamic Acid5% made by sterilization specialists of Mashhad University of Medical Sciences were administered every 6 hours for 5 day

Eligibility

Sex/Gender

All

Age

7 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with Traumatic Hyphema referred to Mashhad Eye "Khatam AlAnbia Hospital"

Exclusion criteria

Exclusion criteria: Microscopic hyphema Globe rupture Patients with systemic diseases such as diabetes mellitus, hypertension Posterior segment pathology except commotio retina coagulopathy and taking anticoagulants drugs history of ophthalmic surgery children under 7years old pregnant women.

Design outcomes

Primary

Measure	Time frame
Rebleeding. Timepoint: Daily for 5 days and two weeks later. Method of measurement: Slit lamp biomicroscopy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkbar Derakhshan

Mashhad University of Medical Sciences

DerakhshanA@mums.ac.ir+98 51 3728 9911

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026