Effect of selenium and n-acethylcysteine antioxidants on superoxide dismutase enzyme.

Comparison of the average superoxide dismutase enzyme in the groups receiving selenium and n-acethylcysteine antioxidants in severe trauma patients admitted to an intensive care unit

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201109049317N1

Enrollment

Registered

2021-05-03

Start date

2019-08-05

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sever Trauma.

Interventions

Intervention 1: Intervention group: Selanase vial 50 mcg in 10 cc.FIRST.Receive selenium in first day 1000 mcg over 24 hours.second day 400 mcg over24 hours.third day 200 mcg over24 hours. Interventio

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age older than 18 year Severe trauma patients need to admit in an Intensive Care Unit

Exclusion criteria

Exclusion criteria: Incomplete demographic information Preexisting conditions Sepsis and organ failure Drug sensitivity

Design outcomes

Primary

Measure	Time frame
Superoxide dismutase. Timepoint: 3 days after drug infusion. Method of measurement: Superoxide Dismutase Assay Kit.	—

Secondary

Measure	Time frame
Organ function. Timepoint: 3 days after drug infusion. Method of measurement: APACHI 2.;Level of concsiousness. Timepoint: 3days after drug infusion. Method of measurement: Glasco Coma Scale.;Duration of hospitalization. Timepoint: Days of hospitalization after drug infusion. Method of measurement: Days of hospitalization.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeili Asadabadi

Kerman University of Medical Sciences

lasadabadi@yahoo.com+98 34 3211 8067

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026