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Evaluation of the relationship between Serum Levels of Total Antioxidants and Vitamin D supplementation in Hemodialysis Patients

Evaluation of the relationship between Serum Levels of Total Antioxidants and Vitamin D supplementation in Hemodialysis Patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201108049311N3
Enrollment
86
Registered
2021-02-06
Start date
2020-12-30
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis patients. Cloudy (hemodialysis) (peritoneal) dialysis effluent

Interventions

Intervention 1: Intervention group: Colecalciferol drug of Iran Hormone Pharmaceutical Company (orally pearl and capsule-like once a week (50000 units) for 12 weeks). Intervention 2: Control group: Pl

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Consent to participate in the study Age range of 15-70 years Dialysis patients undergoing blood dialysis for more than 3 months. Patients undergoing hemodialysis 3 times a week. Patients undergoing blood hemodialysis that their 25-hydroxyvitamin D concentration is less than 30 ng/ml.

Exclusion criteria

Exclusion criteria: Dissatisfaction to participate in the study Patients with active infection Patients with history of renal transplantation Patients with any history of malignancy Presence of hyperphosphatemia (Blood phosphor >7) History of parathyroidectomy

Design outcomes

Primary

MeasureTime frame
Evaluation of lipid profile. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.;Evaluation of serum levels of 25OHD. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.;Evaluation of parathyroid hormone (PTH) levels. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.;Evaluation of Klotho levels. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.;Evaluation of CRP levels. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.;Evaluation of MDA levels. Timepoint: Before intervention and after medication. Method of measurement: Biochemical methods.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamid Taybi Khosroshahi

Tabriz University of Medical Sciences

drtayebikh@yahoo.com+98 41 3336 9331

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026