preterm delivery. Preterm labor with preterm delivery
Conditions
Interventions
Intervention 1: Intervention group: Lactofem capsule (500 mg) made by Iranian zist-takhmir Company will be administered orally and daily from the 16 weeks until the end of pregnancy. Intervention 2: C
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Patient age 18-45 years Gestational age between 16-24 weeks Absence of syphilis, gonorrhea and HIV clinically Having risk factors for preterm delivery in the current pregnancy, including a history of preterm delivery or a second trimester abortion in a previous pregnancy No elective or emergency cerclage Lack of maternal insulin-dependent diabetes mellitus, treatment of hypertension, lupus
Exclusion criteria
Exclusion criteria: Reluctance to participate in the study Failure to complete the course of treatment or use of probiotics Taking drugs that affect the intestinal microbial flora, such as antibiotics Occurrence of any genital or urinary tract infection requires antibiotic treatment during treatment Fetus with congenital malformations and abnormal scan anomalies Clinical chorioamnionitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Premature preterm birth (less than 34 weeks gestation). Timepoint: End of intervention. Method of measurement: Symptom.;Late preterm birth (34-37 weeks gestation). Timepoint: End of intervention. Method of measurement: Symptom. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRaziyeh Vanda
Yasouj University of Medical Sciences
Outcome results
None listed