Evaluation of the effect of sperm preparation by free centrifugation on clinical outcomes in ICSI cycles

Comparison of clinical outcomes between Natural Sperm Sorting (NSS) and Direct Swim Up (DSU) in ICSI program; Assessments of mitocondorial, chromatin integrity and fine morphology (MSOME)

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201104049263N1

Enrollment

Registered

2021-09-13

Start date

2021-09-16

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Control group: sorted sperm with Direct swim up. Intervention 2: Intervention group: Sperms that are isolated by NSS method.

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Non male factor Female with donation cases for homogenization Study groups

Exclusion criteria

Exclusion criteria: Male factor Female factor

Design outcomes

Primary

Measure	Time frame
Fertilization rate. Timepoint: One day after assisted artificial insemination. Method of measurement: Microscopic examination.;Embryo formation rate. Timepoint: 3 days after assisting artificial insemination. Method of measurement: Microscopic evaluation.;Chemical pregnancy rate. Timepoint: One week after the embryo transfer to the uterus. Method of measurement: Blood ßHCG Measurement.	—

Secondary

Measure	Time frame
Clinical pregnancy rate. Timepoint: 7 weeks after embryo transfer to the uterus. Method of measurement: Assessment of cardiovascular formation using ultrasound examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Khalili

Yazd University of Medical Sciences

khalili59@hotmail.com+98 35 3824 8119

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026