The Effects of Anodal tDCS on Incontinency in Patients with Multiple Sclerosis (MS)

The Effects of Short-Term and Long-Term Anodal tDCS over M1 Cortex Concurrent with Pelvic Floor Muscle Training (PFMT) on Pelvic Floor Muscle Function and Incontinency in Patients with Multiple Sclerosis (MS)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201102049234N1

Enrollment

Registered

2020-11-14

Start date

2021-01-20

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group: Anodal tDCS over M1 cortex concurrent group with progressive exercises of pelvic floor muscles. Intervention 2: Intervention group: Anodal sham tDCS over M1 cortex

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women with Definitive Diagnosis of MS with Stable Disease over the Previous 4 Months Definite MS Diagnosis According to the 2010 Revised McDonald Criteria Age Is Between 18 and 45 Years Having Symptoms of Urinary Incontinence Patients Have Received Stable Pharmacological Therapies for the Past 6 Months Patient's Expanded disability status scale (EDSS) Score Should Be Less than 6.5 Patients Have the Cognitive Capacity to Complete the Assessment and Treatment Protocol Minimal Ability to Contract the Pelvic Floor Muscles To Be Willing to Participate in the Study

Exclusion criteria

Exclusion criteria: History of MS Relapse during Treatment Being Pregnant or in the First 6 Months Post-Partum Cesarean Section or Vaginal Delivery within 6 Months Previously to Time of Enrolment Pelvic Organ Prolapse at Vaginal Examination Urinary Tract Infection Having Undergone Surgical Treatment for Urinary Incontinence Having Undergone Prior Physiotherapy for Urinary Incontinence The Presence of Any Other Neurological or Kidney Disease Contraindications of Electrical Stimulation Declining to Participate in the Study Inability to Understand and Comply with the Study Procedures

Design outcomes

Primary

Measure	Time frame
Level of urinary incontinence. Timepoint: Before the intervention, 4 and 6 weeks after the start of intervention and one month after the end of intervention. Method of measurement: International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form.;Pelvic floor muscle function. Timepoint: Before the intervention, 4 and 6 weeks after the start of intervention and one month after the end of intervention. Method of measurement: ultrasonographic device.	—

Measure

Time frame

Level of urinary incontinence. Timepoint: Before the intervention, 4 and 6 weeks after the start of intervention and one month after the end of intervention. Method of measurement: International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form.;Pelvic floor muscle function. Timepoint: Before the intervention, 4 and 6 weeks after the start of intervention and one month after the end of intervention. Method of measurement: ultrasonographic device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFariba Ramezani

Semnan University of Medical Sciences

mona.ramezani.sa@gmail.com+98 23 8502 3332

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026