Effect of Astaxanthin in treatment of PCOS

The Astaxanthin effect on serum inflammatory markers and expression of genes related to ER stress and apoptosis pathway in peripheral blood mononuclear cell in polycystic ovary syndrome women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201029049183N2

Enrollment

Registered

2022-04-12

Start date

2022-04-21

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovarian Syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Intervention group: Astaxanthin consumption. In this group, patients take 12 mg of astaxanthin daily ( in 2 capsules of 6mg twice in the morning and at night) for 6

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Oligo/anovulation (ovulationabnormality) Hyperandrogenism Polycystic ovaries on ultrasound

Exclusion criteria

Exclusion criteria: Pregnancy Adrenal hyperplasia Androgen-secretingtumors Hyperprolactinemia Thyroid dysfunction Diabetes mellitus or glucose tolerance Male infertility factors

Design outcomes

Primary

Measure	Time frame
ER stress and apoptotic factor. Timepoint: Before and 60 days after the intervention. Method of measurement: real time pcr.;Plasma inflammatory factors. Timepoint: Before and 60 days after the intervention. Method of measurement: ELISA KIT.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr.fardin amidi

Tehran University of Medical Sciences

amidifardin@yahoo.com+98 21 6405 3411

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026