Skip to content

Compression of intranasal ketamine, intranasal fentanyl adjunct to intravenous ketorolac on renal colic pain relief

Compression of intranasal ketamine, intranasal fentanyl adjunct to intravenous ketorolac on renal colic pain relief: A Randomized Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201028049179N1
Enrollment
120
Registered
2020-11-02
Start date
2020-09-29
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

renal colic. Unspecified renal colic

Interventions

Intervention 1: Intervention group: first intervention group: Group A: 1 milligram per kilogram intranasal ketamine (maximum 50 milligrams, 25 milligrams in each nostril) and 30 milligrams intravenous

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 64 Years

Inclusion criteria

Inclusion criteria: All patients suspected for renal colic and urolithiasis based on urine analysis and imaging (ultrasonography or CT scan), history and physical examination. Age between 15 to 64

Exclusion criteria

Exclusion criteria: Pregnancy Addiction to opioids and psychedelics Allergy to fentanyl, ketamine and ketorolac Fever (body temperature more than 38°C) and suspicion of pyelonephritis Systolic blood pressure above 180 mm Hg or below 90 mm Hg, respiratory rate below 12 per minute and heart rate above 140 or below 60 History of liver, renal or cardiovascular disease, active peptic ulcer, brain tumors, glaucoma and psychosis Consumption of analgesic drugs in the last 4 hours VAS score below 5 Congestion of both nostrils

Design outcomes

Primary

MeasureTime frame
Severity of renal colic pain according to Visual Analogue Scale score. Timepoint: Initiation of study and 5, 10, 15, 30 and 60 minutes after prescription medication. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Sadat Zebhi Ashkezari

Yazd University of Medical Sciences

Zebhiashkezari@gmail.com+98 35 3272 2673

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026