Effect of Atorvastatin to decrease intensity of clinical manifestations in patient with COVID19

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201028049175N3

Enrollment

100

Registered

2021-01-15

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus Disease 2019 (COVID19). COVID-19, virus identified

Interventions

Intervention 1: Intervention group: Atorvastatin 40 mg tablet orally (or with gavage in intubated patients) will be added to routine treatment protocol for 10 days from first day of hospitalization.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with 18-75 years old Patients with positive PCR test for COVID19 who ara referred to Amiralmomenin and Khansari hospitals of Arak city Patients who have informed consent for entrance into the study.

Exclusion criteria

Exclusion criteria: Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
Duration of having fever. Timepoint: Measuement of body temperature daily from first day to releasing day. Method of measurement: Thermometer.;Duration of having cough. Timepoint: Daily evaluation of having cough from first day to releasing day. Method of measurement: Quastion of patient or his carer.;Atrial oxygen saturation in hospital. Timepoint: Daily evaluation from first day to releasing day. Method of measurement: Pulse oximeter.;Length of hospitaliztion. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Length of ICU stay. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Duration of intubation. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Mortality. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Duration of oxygen therapy. Timepoint: From first day of hospitalization to releasing day. Method of measurement: Patient file.	—

Measure

Time frame

Duration of having fever. Timepoint: Measuement of body temperature daily from first day to releasing day. Method of measurement: Thermometer.;Duration of having cough. Timepoint: Daily evaluation of having cough from first day to releasing day. Method of measurement: Quastion of patient or his carer.;Atrial oxygen saturation in hospital. Timepoint: Daily evaluation from first day to releasing day. Method of measurement: Pulse oximeter.;Length of hospitaliztion. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Length of ICU stay. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Duration of intubation. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Mortality. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Duration of oxygen therapy. Timepoint: From first day of hospitalization to releasing day. Method of measurement: Patient file.

—

Secondary

Measure	Time frame
White blood cell count. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Lymphocyte percentage. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Lactate dehydrogenase level. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Creatine phosphokinase level. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.	—

Measure

Time frame

White blood cell count. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Lymphocyte percentage. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Lactate dehydrogenase level. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.;Creatine phosphokinase level. Timepoint: From first day of hospitalization to releasing day. Method of measurement: patient file.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Kamali

Arak University of Medical Sciences

alikamaliir@yahoo.com086-32222003-8

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026