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Comparison of the efficacy of Atorvastatin and Rosuvastatin in atrial fibrillation incidence after coronary artery bypass graft surgery (CABG)

Comparison of the efficacy of Atorvastatin and Rosuvastatin in atrial fibrillation incidence after coronary artery bypass graft surgery (CABG)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201028049175N2
Enrollment
104
Registered
2021-01-13
Start date
2021-03-10
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Atrial fibrillation after CABG. Condition 2: Atrial fibrillation after CABG. Paroxysmal atrial fibrillation Unspecified complication of cardiac and vascular prosthetic device, implant and graft

Interventions

Intervention 1: Intervention group:Atorvastatin 40 mg tablet orally will be used after surgery when patient can use oral nutrition, daily till 7 days after surgery. Intervention 2: Intervention group:

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All of patients reffered to Amiralmomenin hospital for elective CABG surgery Patients with 40 or more than 40 EF Patients with On-pump method in surgery

Exclusion criteria

Exclusion criteria: Recent MI Using of antiarhythmic drugs especially Amiodarone History of AF Valvular dysfunction Other surgeries with CABG Organic disease (i.e chronic renal failure stage 3 and 4), thyroid dysfunction, immunosuppression, cancer, central nervous system disease, brain vessels disease and history of CerebroVascular Accident, hormonal diseases, rise of liver enzymes) Hypo/hyperkalemia Dialysis (abnormal Cr) Use of anti-inflammatory drugs Psychological disorders

Design outcomes

Primary

MeasureTime frame
Frequency of post CABG atrial fibrillation. Timepoint: As starting drug till 7 days after surgery. Method of measurement: Heart monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Kamali

Arak University of Medical Sciences

alikamaliir@yahoo.com086-32222003-8

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026