Effectiveness of Atorvastatin on reducing of death and illness after catheterization

Effectiveness of Atorvastatin on mortality and morbidity in catheterization procedures (Permcath)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201028049175N10

Enrollment

228

Registered

2021-11-16

Start date

2021-11-18

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications after permanent catheterization (permcath). Other specified complications of cardiac and vascular prosthetic devices, implants and grafts

Interventions

Intervention 1: Intervention group: Patients will receive Atorvastatin (Sobhan daru-Iran) 80 mg tablet 4 hours before surgery and 40 mg after surgery for 6 months daily. Intervention 2: Control group:

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients older than 18 years old Patients who have informed consent Patients who need permanent dialysis Sinus rhythm heart

Exclusion criteria

Exclusion criteria: Patients with chronic atrial fibrillation (AF) Patients with liver failure Patients with using class I and III of anti-arrhythmic drugs Patients with using corticosteroid drugs Patients with history of statin use in control group

Design outcomes

Primary

Measure	Time frame
Frequency of cardiac arrhythmia. Timepoint: During 24 hours after catheterization. Method of measurement: Heart monitoring.;Frequency of myocardial infarction. Timepoint: During 24 hours after catheterization. Method of measurement: Heart monitoring.;Catheter site infection. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Catheter function. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Catheter stenosis. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Mortality. Timepoint: During 24 hours after catheterization. Method of measurement: Number.	—

Measure

Time frame

Frequency of cardiac arrhythmia. Timepoint: During 24 hours after catheterization. Method of measurement: Heart monitoring.;Frequency of myocardial infarction. Timepoint: During 24 hours after catheterization. Method of measurement: Heart monitoring.;Catheter site infection. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Catheter function. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Catheter stenosis. Timepoint: Every 2 weeks till 6 month. Method of measurement: Physical examination.;Mortality. Timepoint: During 24 hours after catheterization. Method of measurement: Number.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Shojaee

Arak University of Medical Sciences

dr.reza.shojaee@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026