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Comparison of the effect of Evening primrose oil with vaginal misoprostol in softening of the cervix before myomectomy hysteroscopy in Yas Hospital

Comparison of the effect of Evening primrose oil with vaginal misoprostol in softening of the cervix in patients candidate for myomectomy hysteroscopy in Yas Hospital 2020-2022: a Randomized Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201028049169N1
Enrollment
118
Registered
2020-11-02
Start date
2020-11-21
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uterine Leiomyoma. Leiomyoma of uterus

Interventions

Intervention 1: Intervention group: 6 hours before hysteroscopy for cervix ripening, 200 micrograms of vaginal misoprostol from Samisaz pharmaceutical company is placed in the posterior part of the va

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: All non-menopausal nulliparous women or Gravid One women with a history of one cesarean section The age group of 25 to 75 years

Exclusion criteria

Exclusion criteria: people with a history of schizophrenia or epilepsy taking phenothiazines, structural cervical abnormalities such as a history of cervical insufficiency, Müllerian anomaly, and history of conization The unwillingness of people to participate in the study Allergy to Evening primrose oil or misoprostol contraindications for Evening primrose oil or misoprostol using such as coagulation disorders or concomitant consumption of anticoagulants drug

Design outcomes

Primary

MeasureTime frame
The cervix dilatation measurement. Timepoint: Once, Before hysteroscopy. Method of measurement: The Hegar dilator size using for hysteroscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Garfami

Tehran University of Medical Sciences

sahar.garfami87@yahoo.com+98 21 8608 9089

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026