Comparison of MA and KA Techniques in TKA

Comparison of Outcomes of Kinematic Alignment and Mechanical Alignment Techniques in Patients with Bilateral Severe Osteoarthritis Who Underwent Single Surgeon Simultaneous Bilateral Primary Total Knee Arthroplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201027049159N1

Enrollment

Registered

2020-10-30

Start date

2017-03-21

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: The first group is the group in which the right knee is replaced by Kinematic alignment method and the left knee is replaced by Mechanical alignment method. In gene

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Sever bilateral osteoarthritis Debilitating bilateral knee pain due to osteoarthritis Age>50 and age<80

Exclusion criteria

Exclusion criteria: Sever underlying diseases which make anesthesia impossible Recurrent UTI BMI50 History of osteomielitis around knee Neuropathic arthropathy Active or recent infection other than knee Pain free nonfunctional osteoarthritis Genu Recurvatum due to muscular disorders Disruption in knee extensor mechanism Active or recent knee infection

Design outcomes

Primary

Measure	Time frame
Knee functional score on the Oxford Knee Questionnaire. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Oxford Knee Score Questionnaire.;Pain rate based on Visual Analogue Scale. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Visual Analogue Scale questionnaire.;Knee Range of Motion. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Goniometer.;Rate of knee joint infection after surgery. Timepoint: 1, 3, 6, 12 month after surgery. Method of measurement: Clinical evaluation and CRP (C-reactive protein) and ESR ((Erythrocyte Sedimentation Rate) level.;Duration of surgery. Timepoint: After surgery. Method of measurement: Duration of tourniquet time in minutes.;Score based on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire.	—

Measure

Time frame

Knee functional score on the Oxford Knee Questionnaire. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Oxford Knee Score Questionnaire.;Pain rate based on Visual Analogue Scale. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Visual Analogue Scale questionnaire.;Knee Range of Motion. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Goniometer.;Rate of knee joint infection after surgery. Timepoint: 1, 3, 6, 12 month after surgery. Method of measurement: Clinical evaluation and CRP (C-reactive protein) and ESR ((Erythrocyte Sedimentation Rate) level.;Duration of surgery. Timepoint: After surgery. Method of measurement: Duration of tourniquet time in minutes.;Score based on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Timepoint: Before surgery, 1, 3, 6, 12 month after surgery. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKeyvan Ramezani

Shahid Beheshti University of Medical Sciences

keyvanramezani@gmail.com+98 21 7343 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026