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Effect of buprenorphine on pain intensity after surgery

Evaluating the effect of preoperative sublingual buprenorphine on pain intensity after lumbar disc surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201026049147N1
Enrollment
78
Registered
2020-12-09
Start date
2018-03-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative pain. Chronic post-thoracotomy pain

Interventions

Intervention 1: Intervention group: Received a single sublingual 2 mg Bupernorphine tablet (manufactured by Jalinous pharmaceutical company) one hour before surgery. Intervention 2: Control group: Rec

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patient candidate for elective discectomy with 1 or 2 lumbar discs With ASA class I and II Age range 35-70 Conscious consent to participate in the study Hypersensitivity to buprenorphine Confirmation of diagnosis by physical examination, CT scan and MRI Patient's willingness to participate in the study and obtaining informed consent

Exclusion criteria

Exclusion criteria: Patient's unwillingness at any time to continue the study Incidence of any uncommon side effects during surgery. Alcohol or drug abuse Opioids use 24 hours prior to intervention Involvement of more than two lumbar disc

Design outcomes

Primary

MeasureTime frame
Opium usage. Timepoint: 0, 2, 4, 6, 12, 24 hours after surgery. Method of measurement: Checklist.

Secondary

MeasureTime frame
Pain severity. Timepoint: 0, 2, 4, 6, 12, 24 hours after surery. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHojat Deilami

Mazandaran University of Medical Sciences

hojatdeilami@gmail.com+98 11 3331 1111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026