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Comparison of probiotics in the prevention of preterm labor

Comparison of vaginal and oral probiotics in the prevention of preterm labor

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201024049128N2
Enrollment
185
Registered
2020-12-19
Start date
2020-12-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labor. Preterm labor

Interventions

Intervention 1: Intervention group: Oral probiotic pills once a day for up to 37 weeks of pregnancy. Intervention 2: Intervention group: Probiotic vaginal capsule once a day for up to 37 weeks of pre

Sponsors

Karaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Intact amniotic membrane No taking probiotics No maternal disease including pyelonephritis, preeclampsia, chronic hypertension, diabetes. Gestational age greater than or equal to 25 weeks Normal cervical length

Exclusion criteria

Exclusion criteria: The mother's unwillingness to be in this study Cervical length less than 3 cm Existence of labor show Effective labor pains Oligohydramnios polyhydramnios placental abruption placenta previa hepatic impairment Existence of abnormal fetal heart rate pattern in monitoring Intrauterine infection

Design outcomes

Primary

MeasureTime frame
Preterm labor. Timepoint: Delivery before 37 weeks. Method of measurement: Medical record.

Secondary

MeasureTime frame
Kind of delivery. Timepoint: After labor. Method of measurement: Medical record.;NICU administration. Timepoint: After birth. Method of measurement: Medical record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBita badehnoosh

Karaj University of Medical Sciences

b_badehnoosh@yahoo.com+98 26 3222 2021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026