Unfavorable cervix.
Conditions
Interventions
Intervention 1: Intervention group: Vaginal Misoprostol. Misoprostol is a prostaglandin E1 analog known to stimulate uterine contractions. In this study 100-microgram tablets were used. In this interv
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Singleton gestation Alive fetus Cephalic presentation Intact membranes Unfavorable cervix (Bishopscore =6) Reassuring fetal heart rate Gestational age=28
Exclusion criteria
Exclusion criteria: Non-cephalic presentation Adequate uterine contractions (3 contractions Lasting for 30sec/10 min) Ruptured membranes Cephalopelvic disproportion Multiple pregnancy Polyhydramnios Estimated fetal weight =4000g or =1800g Placental abruption, Placenta previa Unexplained vaginal bleeding Prior lower segment cesarean section/Scarred uterus Non-reassuring fetal status Clinically detected vaginal infections(exp:genital herpes) or chorioamnionitis Latex or Prostaglandins allergy or any contraindications receiving Prostaglandins, including a history of asthma, glaucoma, or cardiovascular disease Intrauterine fetal death Renal or hepatic failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean time interval from start of induction to delivery. Timepoint: Time of birth. Method of measurement: Clock.;Duration of latent phase. Timepoint: At the end of latent phase. Method of measurement: Clock.;Duration of active phase. Timepoint: At the end of active phase. Method of measurement: clock.;Rate of delivery within 12 hours. Timepoint: At the end of study. Method of measurement: Patient's file.;Rate of delivery within 24 hours. Timepoint: At the end of study. Method of measurement: Patient's file. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cesarean rate. Timepoint: At the end of study. Method of measurement: Patient's file.;Incidence of tachysystole. Timepoint: Continuously. Method of measurement: Cardiotocography.;Incidence of hypertonus. Timepoint: Continuously. Method of measurement: Cardiotocography.;Apgar score. Timepoint: 1 minute and 5 minutes after birth. Method of measurement: Examination of the newborn.;Incidence of meconium passage. Timepoint: At birth. Method of measurement: Examination of the newborn.;Incidence of chorioamnionitis. Timepoint: Every 3 hours. Method of measurement: Physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBita Badehnoosh
Karaj University of Medical Sciences
Outcome results
None listed