Myocardial infarction. Chronic ischemic heart disease
Conditions
Interventions
Intervention 1: Intervention group 1 (HV-HIIT group): A training session on the treadmill at 4 × 4-minute intervals at 90% of HRr with 3 minutes of active recovery at 65% of HRr between intervals and
Sponsors
Khoram-Abad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: MI type 1 and having an ejection fraction of 40% At least six to two years have passed since the diagnosis and angioplasty Be in a stable condition without drug changes In class II, I have cardiac function. Maximum metabolic equivalent to or more than 5 MET
Exclusion criteria
Exclusion criteria: Metabolic diseases such as diabetes and obesity Variable blood pressure Congestive heart failure Dangerous arrhythmias Liver and kidney failure Chronic obstructive pulmonary disease Neuromuscular disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of miR-1. Timepoint: Before and after the intervention. Method of measurement: Real time – PCR.;C-Reactive Protein (CRP). Timepoint: Before and after the intervention. Method of measurement: by using the immunometric assay technique method and ELISA Kit.;Uric acid. Timepoint: Before and after the intervention. Method of measurement: by using the immunometric assay technique method and ELISA Kit.;Expression of miR-208. Timepoint: Before and after the intervention. Method of measurement: Real time – PCR.;Expression of miR-133. Timepoint: Before and after the intervention. Method of measurement: Real time – PCR.;Expression of mRNACapas3. Timepoint: Before and after the intervention. Method of measurement: Real time – PCR.;CK-mb. Timepoint: Before and after the intervention. Method of measurement: by using the immunometric assay technique method and ELISA Kit.;Troponin. Timepoint: Before and after the intervention. Method of measurement: by using the immunometric assay technique method and ELISA Kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life. Timepoint: Before and after the intervention. Method of measurement: Quality of Life Questionnaire.;Ejection fraction. Timepoint: Before and after the intervention. Method of measurement: Echocardiography and Simpson.;Systolic blood pressure. Timepoint: Before and after the intervention. Method of measurement: Digital blood pressure device.;Maximal Oxygen Consumption (peak VO2). Timepoint: Before and after the intervention. Method of measurement: Exercise stress test.;End-systolic volume. Timepoint: Before and after the intervention. Method of measurement: M-mode echocardiography.;Diastolic blood pressure. Timepoint: Before and after the intervention. Method of measurement: Digital blood pressure device.;End-Diastolic volume. Timepoint: Before and after the intervention. Method of measurement: M-mode echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMustafa Cheraghi
Khoram-Abad University of Medical Sciences
Outcome results
None listed