severe pre-eclampsia. Severe pre-eclampsia, third trimester
Conditions
Interventions
Intervention 1: Intervention group: Oral misoprostol manufactured in Aboorehyan pharmacy CO, Iran, give to patients sublingually after C-section it is in combination with conventional treatment that i
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: ALL pregnant mothers with severe pre-eclampsia who referred to the Shahi Kamali educational center in the study period Hospitalization for C-section Gestational age over 35 weeks Having a healthy and alive fetus Cephalic fetus A maximum of 2 previous cesarean sections Complete removal of the placenta after cesarean section The age of 18-45 years
Exclusion criteria
Exclusion criteria: Mothers with coagulation disorders History of maternal blood disorders Chronic hypertension Placental adhesion such as placenta previa and ecrta Placental abruption (overt and covert) Complications or emergency during surgery Eclampsia Mild pre-eclampsia Abnormal placenta History of uterine rupture High bleeding risk Indication for hysterectomy or TL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding volume with gauze counting. Timepoint: Immediately, 1 hour, and 4 hours after C-section. Method of measurement: gauze counting.;Hemoglobin and hematocrit changes. Timepoint: 24 hours after C-section. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMansooreh Sadeghi Afkham
Karaj University of Medical Sciences
Outcome results
None listed