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Effect of two doses of ketorolac in the treatment of acute renal colic pain

Comparison of the effectiveness of two intravenous doses of ketorolac for the treatment of acute renal colic in patients referred to the emergency department

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201018049062N1
Enrollment
160
Registered
2020-11-18
Start date
2020-12-05
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Colic. Calculus of kidney

Interventions

Intervention 1: Intervention group: Ketorolac group with a dose of 15 mg stat. Intervention 2: Intervention group: Ketorolac group with a dose of 30 mg stat.

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 70 Years

Inclusion criteria

Inclusion criteria: All patients over 16 years of age admitted to the emergency department due to renal colic

Exclusion criteria

Exclusion criteria: age older than 70 y/o Women during pregnancy or lactation Gastrointestinal problems such as gastritis, peptic ulcer or acute bleeding Allergy to nonsteroidal anti-inflammatory drugs Unstable vital signs (systolic BP less than 90 or more than 180 mm Hg, HR less than 50 or more than 150) Patients with a history of analgesia

Design outcomes

Primary

MeasureTime frame
Pain intensity score on a numerical pain scale. Timepoint: Measurement of pain intensity at the time of referral (before drug injection), 20, 40 and 60 minutes after drug injection. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Satisfaction with the type of treatment. Timepoint: 60 minutes after receiving the drug. Method of measurement: 5 point scale.;Side effects. Timepoint: 60 minutes after drug injection. Method of measurement: Physical examination.;The need for a life-saving dose. Timepoint: After establishing painlessness. Method of measurement: Frequent administration of morphine rescue dose.;Heart Rate. Timepoint: 20, 40 and 60 minutes after injection. Method of measurement: Number on monitoring.;Average Blood Pressure. Timepoint: 20, 40 and 60 minutes after injection. Method of measurement: Number on monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSheida Mehrdad

Zahedan University of Medical Sciences

sheida.mehrdad@zaums.ac.ir+98 54 3337 2155

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026