Effect of magnesium sulfate and nifedipine in preterm labor

Comparison of magnesium sulfate and nifedipine in treatment of preterm labor in pregnant women with 28-34 weeks of gestational age.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201017049052N1

Enrollment

100

Registered

2020-11-23

Start date

2019-06-01

Completion date

Unknown

Last updated

2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Labor. Preterm labor without delivery, unspecified trimester

Interventions

Intervention 1: Intervention group 1: Nifidipine recipient with an initial dose of 20 mg orally and then every 6 hours for 24 hours. Intervention 2: Intervention group 2: Recipient of 20% magnesium su

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Single fetus pregnancy Pregnancy in 28_34 weeks of gestational age Not in the active phase of labor No contraindication to continue pregnancy

Exclusion criteria

Exclusion criteria: Any situation that makes it impossible to continue the pregnancy Contraindications to the use of Nifedipin or Magnesium sulfate in the patient

Design outcomes

Primary

Measure	Time frame
Delaying preterm delivery for more than 48 hours. Timepoint: Measurement of dilatation and effaceman of the cervix before treatment and 24 hours and 48 hours after treatment. Method of measurement: Manual vaginal examination.	—

Secondary

Measure	Time frame
Drug side effects. Timepoint: Frequently after starting treatment until the end of the dose. Method of measurement: Patient statement and questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Mahdavi

Ahvaz University of Medical Sciences

mina.m349@yahoo.com+98 61 3337 6318

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026