Femur fracture. Unequal limb length (acquired), femur
Conditions
Interventions
Intervention 1: Intervention group: One 4 mg tizanidine tablet orally (made by Galenus) (3 hours prior to single dose anesthesia). Intervention 2: Intervention group: One 25 mg Baclofen tablet orally
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Confirmation of femur fracture candidate diagnosis by orthopedic specialist The patient's desire to participate in the study and gain informed consent Candidate for non-emergency femur surgery and fracture Patients aged 25-70 years No history of allergy to baclofen and tizanidine Absence of bradycardia (HR 2)
Exclusion criteria
Exclusion criteria: Using drug 24 hours before the intervention Occurrence of any unusual complication during surgery and during anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain severity. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Visual Analogue Scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea and vomiting. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire.;Itching. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire.;Dry mouth. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire.;Bradycardia. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire.;Headache and dizziness. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire.;Drowsiness. Timepoint: 2, 4, 6, 12, 24, 48 hours after surgery. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ali Safarpour
Mazandaran University of Medical Sciences
Outcome results
None listed