Skip to content

The effect of atorvastatin on Helicobacter pylori

The effect of atorvastatin on Helicobacter pylori quadruple diet

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201014049020N1
Enrollment
210
Registered
2021-01-13
Start date
2020-11-21
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori.

Interventions

Intervention 1: Intervention group: Intervention group 1 in addition to the quadruple diet (including two amoxicillin 500 mg twice daily, tinidazole 500 mg twice daily, two bismuth 120 mg twice daily

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age over 45 years with dyspepsia Age less than 45 years with dyspepsia along with other risk factors Treated resistant dyspepsia History of gastric ulcer History of MALT on a pathology study

Exclusion criteria

Exclusion criteria: Negative results for urease testing of tissue samples unwillingness to participate in the study lack of access to complete information from the file Patient's unwillingness to undergo relevant tests patient's lack of access to medication contraindications for upper gastrointestinal endoscopy sensitivity to tinidazole and amoxicillin and bismuth and pantoprazole or atorvastatin risk factor for endoscopy leading to cardiovascular disease history of surgery Gastrointestinal or gastrointestinal cancers people banned from taking atorvastatin (such as pregnancy and lactation, liver failure and myopathies)

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori infection. Timepoint: 4 to 6 weeks after starting treatment with quadruple diet of Helicobacter pylori plus atorvastatin. Method of measurement: Endoscopic biopsy, urea breath test, rapid urease test, fecal antigen test.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsaeed mehrabani

Bandare-abbas University of Medical Sciences

saeed.dr68@yahoo.com+98 76 4438 0177

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026