Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Existence of pain and other clinical signs of knee osteoarthritis and pain with a VAS score of at least 4 due to knee osteoarthritis during last month Age between 45 to 70 years old Absence of any periarticular disease around the target joint
Exclusion criteria
Exclusion criteria: Diabetes Mellitus Rheumatologically and collagen vascular disorders (eg; gout and lupus) Radiculopathy Nerve injuries and neuropathy Brucellosis BMI more than 42 Knee replacement on the affected side History of trauma and joint fracture Severe deformity of the lower extremities Bleeding disorders Inability to communicate History of allergic reactions to the used drugs History of intraarticular or periarticular injections at the affected joint in the last 3 months History of significant liver, kidney and cardiopulmonary disorders Pregnancy Malignancy Use of anticoagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain due to knee osteoarthritis. Timepoint: Before starting the intervention; 2, 4, 8, &12 weeks later. Method of measurement: Visual analog scale; Western Ontario and McMaster Universities Arthritis Index; Oxford knee scale; Patient satisfaction. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient function. Timepoint: Before starting the intervention; 2, 4, 8, &12 weeks later. Method of measurement: Visual analog scale.;Patient function. Timepoint: Before starting the intervention; 2, 4, 8, &12 weeks later. Method of measurement: Western Ontario and McMaster Universities Arthritis Index.;Patient function. Timepoint: Before starting the intervention; 2, 4, 8, &12 weeks later. Method of measurement: Oxford knee scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Shiraz University of Medical Sciences