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The effect of amniotic membrane and collagen membrane in guided bone regeneration in implant treatment

Comparison of effects of amniotic membrane with collagen membrane in guided bone regeneration in dental implant surgery: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201012049004N1
Enrollment
20
Registered
2020-11-01
Start date
2018-09-23
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

3-wall intrabony defects in jaws. Osseointegration failure of dental implant

Interventions

Intervention 1: Intervention group (amniotic membrane group): The bone defect was filled with bone graft (Cerabone, GmbH, Germany) before placing the implant (Biohorizons, BioHorizons IPH ),then it wa

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient referred to the implant department of the Mashhad Dental School Candidate for dental implant Having 3-wall intrabony defect

Exclusion criteria

Exclusion criteria: The presence of any kind of systemic diseases The presence of any kind of local factors that might impede the natural healing process of the tissue

Design outcomes

Primary

MeasureTime frame
The amount of bone formed on the implant. Timepoint: Intervals of 12 weeks (in the mandible) and 16 weeks (in the maxilla) after stage 2 surgery. Method of measurement: Clinically determined by the percentage of exposed implant threads in the second stage of surgery.;Implant success rate. Timepoint: At intervals of 12 weeks (in the mandible) and 16 weeks (in the maxilla) after surgery. Method of measurement: Implant success rate is determined by reflection frequency analysis (RFA) test using Osstell Mentor (Integration Diagnostics Ltd., Göteborg, Sweden) as well as the application of a reverse torque force of 35 N / cm by the reverse mode of the implant surgery engine and angle 20: 1, It is measured during the second stage of implant surgery. In the osstell mentor device, according to osseointegration a number between 1 and 100 is shown. This number is the Implant Stability Quotient(ISQ) . The higher the ISQ displayed by the device, the higher the degree of integration. In evaluation by reverse torque force, success is expressed as stable and implant failure as unstable.

Secondary

MeasureTime frame
Periodontal tissue healing rate on implant. Timepoint: At 1, 2 and 4 weeks after surgery. Method of measurement: periodontal tissue healing rate is expressed as the absence of membrane and bone graft exposure(A), only membrane exposure (B), or membrane and bone graft exposure (C).;The incidence of infection in the surgical area. Timepoint: At 1, 2 and 4 weeks after surgery. Method of measurement: The incidence of infection in the area is measured and expressed as the presence (+) or absence (-) of infection according to the symptoms of infection in the area (swelling, pain, persistent erythema and secretion of pus).;Patients' postoperative pain. Timepoint: In the first, third and tenth day after surgery. Method of measurement: The amount of pain after surgery of the patient is recorded using a VAS scale in a questionnaire designed for this purpose. In this scale, the amount of pain is classified from 0 to 10 based on the severity of pain.0 is the absence of pain and 10 is the presence of the most severe pain possible.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Gholami

Mashhad University of Medical Sciences

GholamiMH@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026