Cirrhosis of liver. Unspecified cirrhosis of liver
Conditions
Interventions
Intervention 1: Intervention group: At first, all patients are prescribed 2 micrograms per kilogram of fentanyl. Then patients in the first intervention group (M), Midazolam (Elixir Company) is prescr
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Diagnosed liver patients (child Pugh class A or B and MELD = 24) that came for endoscopy and routine screening for varices.
Exclusion criteria
Exclusion criteria: Diagnosed allergies or reaction to sedative materials Suffering from significant respiratory diseases or respiratory tract abnormalities Active neurological disorders such as hepatic encephalopathy Advanced liver failure, decompensated (CP score > 10, MELD > 24, or child Pugh class C) Use of alcohol or unauthorized drugs Consumption of the sedative and narcotic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effectiveness of the midazolam and propofol in sedation. Timepoint: Immediately after Infusion, 1s minute, 5th minute, at recovery. Method of measurement: Designed checklist based on similar studies.;Hemodynamic changes include blood pressure, heart rate, respiration rate, and blood oxygen levels. Timepoint: Immediately after Infusion, 1s minute, 5th minute, at recovery. Method of measurement: Using pulse oximetry and blood pressure monitor.;Sedation time and duration of sedation. Timepoint: At the duration of the study. Method of measurement: Ramsay standard criteria and checklist prepared.;Patient stays in recovery duration and discharge based on Aldrete Score. Timepoint: At the duration of the study. Method of measurement: Aldrete Score standard checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSepideh Besaratdar
Bandare-abbas University of Medical Sciences
Outcome results
None listed