Comparison of the postoperative analgesia effect of the combination of Ibuprofen and paracetamol with the combination of Morphine and paracetamol in open prostatectomy surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201011048988N1

Enrollment

Registered

2020-12-12

Start date

2020-11-16

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open prostatectomy. Erectile dysfunction following simple prostatectomy

Interventions

Intervention 1: First Intervention group: received 30 mg / kg body weight of Ibuprofen plus 35 mg per kg of body weight paracetamol. Intervention 2: Intervention group: received 0.1 mg / kg body weigh

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: All candidate patients for open prostatectomy.

Exclusion criteria

Exclusion criteria: Drug use, narcotic drugs or psychiatric drugs Renal failure Hepatic failure Gastrointestinal disease Opioid, Ibuprofen and paracetamol allergy Spinal anesthesia contraindication General anesthetic contraindication Failure of spinal anesthesia and switch to general anesthesia Respiratory depression while receiving a pump of pain.

Design outcomes

Primary

Measure	Time frame
Severity of postoperative pain. Timepoint: 4, 8, 12, 24, 36 and 48 hours after surgery. Method of measurement: Visual Analogue Scale.;Sedation. Timepoint: 4, 8, 12, 24, 36 and 48 hours after surgery. Method of measurement: Ramssay score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Hajinejad

Islamic Azad university of Zahedan

Zahra.Hnd@gmail.com+98 54 3341 9432

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026