The effect of compound honey syrup on chronic sinusitis in cystic fibrosis patients

The effect of compound honey syrup on clinical manifestations of chronic sinusitis in cystic fibrosis (CF) patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201009048976N1

Enrollment

Registered

2021-01-23

Start date

2020-11-21

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cystic fibrosis. Cystic fibrosis

Interventions

Intervention 1: Intervention group: In addition to all the standard and required medicines for the patient, in the experimental group, compound honey syrup is also prescribed. Consumption of compound

Eligibility

Sex/Gender

All

Age

6 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with cystic fibrosis with clinical signs of sinusitis over 6 years of age who refer to the pulmonary Clinic of Mofid Children's Hospital and enter the study with the informed consent of the parents of children and children over 6 years of age.

Exclusion criteria

Exclusion criteria: Patients with cystic fibrosis under 6 years of age referred to the pulmonary Clinic of the Mofid Children's Hospital, lack of clinical signs of sinusitis, patients in need of hospitalization and patients with increased cough, sputum and fever, and patients with underlying conditions such as allergic bronchopulmonary aspergillosis(ABPA) and Tuberculosis are not included in the study.

Design outcomes

Primary

Measure	Time frame
Runny nose. Timepoint: At the beginning of the study(Before starting the intervention), the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Nasal obstruction. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Ear fullness. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Dizziness. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Ear pain. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Facial pain/pressure. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.	—

Measure

Time frame

Runny nose. Timepoint: At the beginning of the study(Before starting the intervention), the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Nasal obstruction. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Ear fullness. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Dizziness. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Ear pain. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.;Facial pain/pressure. Timepoint: At the beginning of the study, the end of the Sixth and twelfth week. Method of measurement: SNOT questionnair.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsamiraborhani

Shahid Beheshti University of Medical Sciences

samiraborhani@yahoo.com+98 21 8877 3521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026