Skip to content

The effect of ondansetron on the prevention of hypotension after spinal anesthesia

Effect of intravenous ondansetron in comparison with placebo on prevention of hypotension after spinal anesthesia in patients undergoing lower limb orthopedic surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20201006048947N1
Enrollment
100
Registered
2020-10-21
Start date
2020-10-22
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotention induced by spinal anesthesia.

Interventions

Intervention 1: Intervention group: Patients are among the candidates for orthopedic surgery for spinal anesthesia who have no contraindications to spinal anesthesia and have been fasting for at least

Sponsors

Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidates for orthopedic surgery by spinal anesthesia at Peymanieh Hospital in Jahrom Satisfaction of the person to participate in the study age between 18 to 65 years

Exclusion criteria

Exclusion criteria: Patients with hypertension weight more than 100 kg motion sickness cardiac and liver desease and migrain allery to ondansetron drugs using any drugs that change blood pressure or hear rate and any drugs that effects by serotonin receptor

Design outcomes

Primary

MeasureTime frame
Percentage of people with hypotension. Timepoint: Blood pressure measurement during the first 10 minutes, every 3 minutes and then every 5 minutes until the end of 30 minutes of spinal anesthesia. Method of measurement: Measurement with heart monitoring device.

Secondary

MeasureTime frame
Percentage of people with decreased heart rate. Timepoint: during the first 10 minutes, every 3 minutes and then every 5 minutes until the end of 30 minutes of spinal anesthesia. Method of measurement: Measuring heart rate with a heart rate monitor.;Percentage of people with pruritus after spinal anesthesia. Timepoint: Every 10 minutes after spinal anesthesia. Method of measurement: by asking the patient.;Percentage of people with nausea after spinal anesthesia. Timepoint: Every 10 minutes after spinal anesthesia. Method of measurement: by asking the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasim Nabizadeh

Jahrom University of Medical Sciences

Nassimnabizadeh@gmail.com+98 54 0022 3275

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026