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Effect of Growth Hormone on Improve Pregnancy Rate in Women with poor ovarian response

Effect of Growth Hormone on Improve Pregnancy Rate in Women with poor ovarian response

Status
Recruiting
Phases
Phase 3
Study type
Observational
Source
IRCT
Registry ID
IRCT20201003048912N2
Enrollment
124
Registered
2021-02-20
Start date
2020-06-21
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with poor ovarian response. Female infertility

Interventions

Intervention 1: Intervention group: Patients will receive 4 units of subcutaneous growth hormone of Sinagen Company from the 21st day of menstruation, one month before the start of cycle to the day of
36 hours after trigger injection, they will be punctured and according to endometrial conditions, they will routinely be undergone frozen or fresh embryo transfer. Intervention 2: Control group: Patie
36 hours after trigger injection, they are punctured and according to endometrial conditions, they are routinely undergone to frozen or fresh embryo transfer.

Sponsors

Avicenna University Jihad Infertility Center Avicenna
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age less than 40 years, Normal karyotype, Normal thrombophilia (having two or less than two positive tests for thrombophilic heterozygotes) Formation of 5 embryos (more than 3 embryos with good quality) Patients with poor ovarian response (history of an ovulation stimulation cycle with less than 4 oocytes and AMH <1.1 and FSH <20) in infertile women referred to Ibn Sina Infertility Treatment Center

Exclusion criteria

Exclusion criteria: Endometriosis disease Severe oligospermia (morphology count <1%) Patients with hydrosalpinx History of ovarian surgery Underlying disease such as kidney and liver and diabetes and thyroid autoimmune Allergic local reactions and benign increase in intracranial pressure

Design outcomes

Primary

MeasureTime frame
Pregnancy rate. Timepoint: Three months after taking the drug. Method of measurement: The number of patients with BHCG positive is divided by the number of patients who had fetus transfer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mina Ataei

Avicenna University Jihad Infertility Center

Atlee.mina@yahoo.com+98 21 2243 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026