cervical ripening.
Conditions
Interventions
Intervention 1: In the first group, single dose of 40 mg of isosorbide mononitrate from Aria drug will be placed vaginally in the posterior fornix by the researcher. Intervention 2: In the second gro
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
21 Years to 30 Years
Inclusion criteria
Inclusion criteria: Includes 37-40 weeks gestation live fetus Noli Par single fetus cephalic intact membranes under two bishop scores fetal weight less than 4 kg normal fetal health monitoring result no uterine contractions There were no systemic problems in the history and clinical examination.
Exclusion criteria
Exclusion criteria: Abnormality of fetal appearance with pelvis or non-cephalic presence of uterine scar previous history of cesarean section history of cervical cone (conization) polyhydramnios history of drug allergy contraindications to vaginal delivery aginal bleeding during third trimester placenta previa multiple pregnancy suspected fetal abnormality bishop score above 3 uterine contractions uncertain NST chorioamnionitis history of asthma active genital herpes any contraindications to induction of labor systolic pressure less than 90 Cardiovascular disease severe preeclampsia alcoholism history of headache
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cervical ripening. Timepoint: 24 hours after the start of the study. Method of measurement: vaginal examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of the first phase of labor (including latent and active phase). Timepoint: During the study. Method of measurement: Observation and examination.;Duration of the second stage of labor (from complete dilatation to fetal delivery ). Timepoint: During the study. Method of measurement: Observation and examination.;Duration of the third stage of labor (from the time of embryo departure to complete placental abruption). Timepoint: During the study. Method of measurement: Observation and examination.;Method of childbirth. Timepoint: During the study. Method of measurement: Observation and examination.;Maternal complications (headache, nausea, vomiting and dizziness). Timepoint: During the study. Method of measurement: Observation and examination.;Neonatal outcomes (first and fifth minute Apgar score, umbilical cord PH, neonatal hospitalization in intensive care unit). Timepoint: During the study. Method of measurement: Observation and examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahnaz Tajpour
Tehran University of Medical Sciences
Outcome results
None listed