effect of dexamethasone and bupivacaine in reduction of pain and disability after discectomy

Efficacy of intraoperative epidural dexamethasone and bupivacaine in reduction of pain and disability following lumbar discectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201003048906N1

Enrollment

Registered

2021-03-01

Start date

2019-11-22

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar disc herniation. Other intervertebral disc degeneration, lumbar region

Interventions

Intervention 1: Intervention group: Gelfom is soaked with 2cc dexamethason and 4cc bupivacain (0.5 % solution) aplied on hurted root. Intervention 2: Control group: Gelfom is soaked with 6cc normal sa

Eligibility

Sex/Gender

All

Age

17 Years to 75 Years

Inclusion criteria

Inclusion criteria: patient with unilateral single level disc herniation

Exclusion criteria

Exclusion criteria: Previous same level surgery Multilevel disc herniation Spine instability Qauda equina syndrome Spinal kyphosis and scoliosis Spinal modic change and infection

Design outcomes

Primary

Measure	Time frame
Lower limb and back pain. Timepoint: Preoperation and 3,6,12, and 24 hours postoperation. Method of measurement: Visual Analoge Scale.;Disability score. Timepoint: befor surgery and 1 and 6 month after surgery. Method of measurement: Oswestry Disability Index.	—

Secondary

Measure	Time frame
Use of opium dose. Timepoint: 24 hours after surgery. Method of measurement: Base of milligram.;Hospitalization period. Timepoint: Period after surgery. Method of measurement: Number of days.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAidin Shakeri

Arak University of Medical Sciences

saebiradreza@gmail.com+98 86 3222 2004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026