The effect of pethidine, ketrolac and the combination of ketorolac and diazepam on low back pain

Comparison between the effect of pethidine, ketorolac and ketorolac-diazepam combination in reducing pain in patients with acute low back pain referred to the emergency department

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201003048903N1

Enrollment

Registered

2020-10-21

Start date

2019-10-25

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

low back pain. Other chronic pain

Interventions

Intervention 1: Intervention group: The first group consisted of 30 patients with low back pain who received 50 mg of pethidine (intravenously). Intervention 2: Intervention group: The second group co

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients who refer to the emergency department of Peymanieh Hospital in Jahrom due to acute low back pain in 2019-2020. Informed consent to attend the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Heart rate per minute. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' heart rate was measured at the time before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: The heart rate of patients in this study was measured by a nurse in the emergency department and a monitor installed in the emergency department.;The amount of oxygen saturation in the blood. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' blood oxygen saturation was measured at the time before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. . Method of measurement: Patients' blood oxygen levels were measured using a monitor installed in the emergency department.;Pain. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' pain was measured in the time periods before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: Pain variable was measured in this study using Visual Analogue Scale.;Blood pressure. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' blood pressure was measured in the time periods before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: In this study, blood pressure was measured using a manual blood pressure monitor and a cuff monitoring device.	—

Measure

Time frame

Heart rate per minute. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' heart rate was measured at the time before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: The heart rate of patients in this study was measured by a nurse in the emergency department and a monitor installed in the emergency department.;The amount of oxygen saturation in the blood. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' blood oxygen saturation was measured at the time before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. . Method of measurement: Patients' blood oxygen levels were measured using a monitor installed in the emergency department.;Pain. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' pain was measured in the time periods before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: Pain variable was measured in this study using Visual Analogue Scale.;Blood pressure. Timepoint: In this study, the effect of pethidine, ketrolac and ketrolac-diazepam combination on patients' blood pressure was measured in the time periods before injection, immediately after injection, 5, 10, 20, 60 and 90 minutes after injection. Method of measurement: In this study, blood pressure was measured using a manual blood pressure monitor and a cuff monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactEsmaeal Rayat Dost

Jahrom University of Medical Sciences

e.rayat.dost@gmail.com+98 71 5433 6085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026