Evaluation of the effect of Domperidone in the prevention of lung infection in patients with stroke

Evaluation of the effect of Domperidone in the prevention of pneumonia in patients with stroke

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20201001048896N1

Enrollment

170

Registered

2020-12-23

Start date

2021-01-04

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Pneumonia in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Take Dompiridone 10 mg tablet every 12 hours during hospitalization. Intervention 2: Control group: Take placebo tablet every 12 hours during hospitalization.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Clinical signs of acute stroke Radiological findings of acute stroke

Exclusion criteria

Exclusion criteria: Underlying lung disease Lung structural disorders Recent use of prokinetics Pregnancy History of previous pneumonia Immunosuppression

Design outcomes

Primary

Measure	Time frame
Clinical signs. Timepoint: At admission, 48 hours after taking the drug, at discharge. Method of measurement: Physical examination.	—

Secondary

Measure	Time frame
Requires intubation. Timepoint: Duration of hospitalization. Method of measurement: Physical examination.;Duration of hospitalization. Timepoint: Patient discharge day. Method of measurement: Physical examination.;Start feeding orally. Timepoint: During the patient's hospitalization. Method of measurement: Physical examination.;Nutrition tolerance. Timepoint: During the patient's hospitalization. Method of measurement: Physical examination.	—

Measure

Time frame

Requires intubation. Timepoint: Duration of hospitalization. Method of measurement: Physical examination.;Duration of hospitalization. Timepoint: Patient discharge day. Method of measurement: Physical examination.;Start feeding orally. Timepoint: During the patient's hospitalization. Method of measurement: Physical examination.;Nutrition tolerance. Timepoint: During the patient's hospitalization. Method of measurement: Physical examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaieh Kiani Majd

Qazvin University of Medical Sciences

somaiehkiani7@gmail.com+98 28 3333 2931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026