Knee osteoarthritis. Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting i
Conditions
Interventions
Intervention 1: The first intervention group: In this group, PRP injection will be done five times in the amount of 3 ml (two weeks apart) in the patients knee. The centrifuge device manufactured by N
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Mild to moderate osteoarthritis (OA) (2 or 3) as diagnosed by an orthopedic surgeon based on the Kellgren-Lawrence Grading Scale (KL) No inflammatory and bleeding disorders No rheumatoid arthritis No endocrine and metabolic diseases Imbalance and limping No pregnancy not perform procedures such as Arthrocentesis in the last six months No joint surgery last year Willingness to participate in the study
Exclusion criteria
Exclusion criteria: Failure to complete the course of treatment Participant withdrawal from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: Before treatment and 1, 3, and 6 months after treatment. Method of measurement: Numerical Rating Scale (NRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Disability. Timepoint: Before treatment and 1, 3, and 6 months after treatment. Method of measurement: The Western Ontario and McMaster Universities Arthritis Index (WOMAC).;Quality of life. Timepoint: Before treatment and 3, and 6 months after treatment. Method of measurement: 36-Item Short Form Survey (SF-36). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Shaygan
Shiraz University of Medical Sciences
Outcome results
None listed